The Academic Freedom in Constitutions dataset is a new resource that empirically maps constitutional guarantees of the freedom of science, of academic freedom, and of university autonomy in 203 countries, spanning the period from 1789 to 2022. While the topic of academic freedom has been gaining increasing prominence in political and legal research over the past decade, it is so far largely absent from the comparative constitutional literature. However, its global codification process holds interesting insights for the study of international norm diffusion, both with respect to its functional connection to higher education development and its distinct constitutional genealogies. The paper first introduces the dataset and explains how it is different from previous coding efforts, before discussing its significance and potential contributions to the comparative legal literature, political science, and other research.