dc.contributor.author
Meyer, Alexander
dc.contributor.author
Greve, Dustin
dc.contributor.author
Unbehaun, Axel
dc.contributor.author
Kofler, Markus
dc.contributor.author
Kukucka, Marian
dc.contributor.author
Klein, Christoph
dc.contributor.author
Knierim, Jan
dc.contributor.author
Emmert, Maximilian Y.
dc.contributor.author
Falk, Volkmar
dc.contributor.author
Kempfert, Jörg
dc.contributor.author
Sündermann, Simon H.
dc.date.accessioned
2022-02-24T11:28:25Z
dc.date.available
2022-02-24T11:28:25Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/34141
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-33859
dc.description.abstract
Background:
The aim of this study was to evaluate the impact of transcatheter aortic valve implantation (TAVI) on mitral valve geometry and function.
Methods:
Eighty-four patients underwent TAVI. Forty-four (52%) patients received a balloon-expandable valve and 40 (48%) were implanted with a self-expandable valve. All patients underwent three-dimensional-volumetric transesophageal echocardiography of the mitral valve before and immediately after TAVI. A dedicated software was used for assisted semiautomatic measurement of mitral annular geometry.
Results:
During systole, the anterior to posterior (AP) diameter was significantly reduced after the procedure (3.4 ± 0.5 cm vs 3.2 ± 0.5 cm; P < .05). The mitral annular area (10.8 ± 2.8cm2 vs 9.9 ± 2.6cm2; P < .05) as well as the tenting area (1.6 ± 0.7 cm2 vs 1.2 ± 0.6 cm2; P < .001) measured at mid-systole were reduced after TAVI. Diastolic measures were similar. Patients treated with balloon-expandable valves showed a significantly larger reduction in the AP diameter compared to self-expandable valves (−0.25 cm vs −0.11 cm; P < .05). The reduction of the annular area was higher in the balloon-expandable group (−1.2 ± 1.59 vs −0.22 ± 1.41; P < .05). Grade of mitral regurgitation did improve or remained stable after TAVI.
Conclusion:
TAVI significantly impacts the mitral valve and mitral annular geometry and morphology. The choice of the prosthesis (balloon- vs self-expandable) may be relevant for those changes.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
3D echocardiography
en
dc.subject
aortic valve replacement
en
dc.subject
mitral annular geometry
en
dc.subject
mitral regurgitation
en
dc.subject
transcatheter aortic valve implantation (TAVI)
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Transcatheter aortic valve implantation and its impact on mitral valve geometry and function
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1111/jocs.14734
dcterms.bibliographicCitation.journaltitle
Journal of Cardiac Surgery
dcterms.bibliographicCitation.number
9
dcterms.bibliographicCitation.originalpublishername
Wiley
dcterms.bibliographicCitation.pagestart
2185
dcterms.bibliographicCitation.pageend
2193
dcterms.bibliographicCitation.volume
35
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
DEAL Wiley
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32652711
dcterms.isPartOf.issn
0886-0440
dcterms.isPartOf.eissn
1540-8191