dc.contributor.author
Li, Erqin
dc.contributor.author
Krsmanovic, Aleksandra
dc.contributor.author
Ballhausen, Max-Bernhard
dc.contributor.author
Rillig, Matthias C.
dc.date.accessioned
2022-01-20T12:04:04Z
dc.date.available
2022-01-20T12:04:04Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/32934
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-32660
dc.description.abstract
Anthropogenic disturbances pose a multitude of novel challenges to ecosystems. While many experiments have tested effects using abrupt treatment applications, most environmental changes in fact are gradual. Since ecosystem responses might be highly dependent on the temporal nature of stressors, it is crucial to differentiate the effects of abrupt vs gradual treatment application. Antifungal agents, which are widely used in disease control both for humans and in agriculture, are becoming a new class of environmental contaminants. In this study, we examined the effect of a sub-lethal application of one antifungal agent, amphotericin B. We applied different rates of delivery, e.g. gradual and abrupt, and monitored biomass and sporulation of the model fungus Neurospora crassa in a batch culture. Our results demonstrate that: (i) the effect size difference between abrupt and gradual treatments is fungal growth stage dependent and (ii) the gradual treatment clearly had a higher sporulation level compared with all types of abrupt treatments. Our findings highlight the importance of considering the rate of change in environmental change research and point to a new research direction for future global change studies. Furthermore, our results also have important implications for avoiding treatment-induced spore production in agriculture and medical practise.
en
dc.format.extent
9 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by-nc/4.0/
dc.subject
antifungal agents
en
dc.subject
abrupt treatment
en
dc.subject
environmental change
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie
dc.title
Fungal response to abruptly or gradually delivered antifungal agent amphotericin B is growth stage dependent
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1111/1462-2920.15797
dcterms.bibliographicCitation.journaltitle
Environmental Microbiology
dcterms.bibliographicCitation.number
12
dcterms.bibliographicCitation.pagestart
7701
dcterms.bibliographicCitation.pageend
7709
dcterms.bibliographicCitation.volume
23
dcterms.bibliographicCitation.url
https://doi.org/10.1111/1462-2920.15797
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Biologie
refubium.funding
DEAL Wiley
refubium.note.author
Die Publikation wurde aus Open Access Publikationsgeldern der Freien Universität Berlin gefördert.
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
1462-2920
refubium.resourceType.provider
WoS-Alert