In this thesis we construct and study the moduli of hypersurfaces in toric orbifolds. A hypersurface in a variety X is an effective Weil divisor. Explicitly, we construct a quasi- projective coarse moduli space in the category of schemes of quasismooth hypersurfaces in certain toric orbifolds. Such a moduli space has the property that each geometric point represents a hypersurface of a given class up to change of Cox coordinates. Such schemes are constructed as quotients of algebraic group actions. We also examine the moduli spaces in low dimensions and degrees.