dc.contributor.author
Sifft, Kevin C.
dc.contributor.author
Geus, Dominik
dc.contributor.author
Mukampunga, Caritas
dc.contributor.author
Mugisha, Jean Claude
dc.contributor.author
Habarugira, Felix
dc.contributor.author
Fraundorfer, Kira
dc.contributor.author
Bayingana, Claude
dc.contributor.author
Ndoli, Jules
dc.contributor.author
Umulisa, Irenee
dc.contributor.author
Karema, Corine
dc.contributor.author
von Samson-Himmelstjerna, George
dc.contributor.author
Aebischer, Toni
dc.contributor.author
Martus, Peter
dc.contributor.author
Sendegeya, Augustin
dc.contributor.author
Gahutu, Jean Bosco
dc.contributor.author
Mockenhaupt, Frank P.
dc.date.accessioned
2018-06-08T10:57:08Z
dc.date.available
2017-01-13T13:53:37.754Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/21384
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-24678
dc.description.abstract
Background Plasmodium infection and malaria in school children are
increasingly recognized as a relevant public health problem, but data on
actual prevalence and health consequences are insufficient. The present study
from highland southern Rwanda aimed at estimating infection prevalence among
children attending school, at identifying associated factors and at assessing
the clinical consequences of these infections. Methods In a survey including
12 schools in the Huye district of Rwanda, 1089 children aged 6–10 years were
clinically and anthropometrically examined, malaria parasites were diagnosed
by microscopy and PCR, haemoglobin concentrations were measured, and socio-
economic and behavioural parameters as well as medical histories were
obtained. Results Upon examination, the vast majority of children was
asymptomatic (fever 2.7%). Plasmodium infection was detected in 22.4%
(Plasmodium falciparum, 18.8%); 41% of these were submicroscopic. Independent
predictors of infection included low altitude, higher age, preceding
antimalarial treatment, and absence of electricity or a bicycle in the
household. Plasmodium infection was associated with anaemia (mean haemoglobin
difference of −1.2 g/dL; 95% CI, −0.8 to −1.5 g/dL), fever, underweight,
clinically assessed malnutrition and histories of fever, tiredness, weakness,
poor appetite, abdominal pain, and vomiting. With the exception of
underweight, these conditions were also increased at submicroscopic infection.
Conclusion Malaria infection is frequent among children attending school in
southern highland Rwanda. Although seemingly asymptomatic in the vast majority
of cases, infection is associated with a number of non-specific symptoms in
the children´s histories, in addition to the impact on anaemia. This argues
for improved malaria surveillance and control activities among school
children.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft
dc.title
Asymptomatic only at first sight
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Malaria Journal. - 15 (2016), Artikel Nr. 553
dc.title.subtitle
malaria infection among schoolchildren in highland Rwanda
dcterms.bibliographicCitation.doi
10.1186/s12936-016-1606-x
dcterms.bibliographicCitation.url
http://malariajournal.biomedcentral.com/articles/10.1186/s12936-016-1606-x
refubium.affiliation
Veterinärmedizin
de
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000026147
refubium.note.author
Der Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000007531
dcterms.accessRights.openaire
open access