International Framework Agreements (IFAs) represent a still small but growing and particularly interesting contribution to the global regulation of employment relations. IFAs enable global union federations (GUFs) to become actively involved in co-designing employment relations within transnational corporations (TNCs) and their global production networks. Based upon theoretical insights into the challenges of transferring practices in and across organizations, we present and discuss a model of practice transfer for global production networks based on empirical data from a content analysis of IFAs and from interviews with representatives of TNCs, GUFs, and other experts. Our study contributes to an organizational theory of practice transfer. But more importantly, it aims at a better integration of IHRM and international industrial relations by looking more closely at the particular role of GUFs as external actors.