This paper advances Picot and Baumann’s (2009) central paper on how organization and management theory (OMT) can enhance business infor-mation systems engineering (BISE). In particular, we extend their focus in three ways. We introduce the industry and inter-organizational relations as levels of analysis, which are of interests to BISE and we show specific methods to ad-vance the links between OMT and BISE. We exemplify these points by a case study on BreatheCorp., a multinational company that recently entered into the provision of eHealth-based ventilation care services in Germany. Through our empirical study, we can also contribute to theorizing the role of context for in-ter-organizational information systems (IOIS).