Title:
Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids
Author(s):
Könning, Daniel; Olbrisch, Tobias; Sypaseuth, Fanni D.; Tzschucke, C. Christoph; Christmann, Mathias
Year of publication:
2014
Available Date:
2014-10-16T08:39:48.808Z
Abstract:
An oxidation of allylic and benzylic alcohols to the corresponding carboxylic
acids is effected by merging a Cu-catalyzed oxidation using O2 as a terminal
oxidant with a subsequent chlorite oxidation (Lindgren oxidation). The
protocol was optimized to obtain pure products without chromatography or
crystallization. Interception at the aldehyde stage allowed for
Z/E-isomerization, thus rendering the oxidation stereoconvergent with respect
to the configuration of the starting material.
Part of Identifier:
ISSN (print): 1359-7345
DDC-Classification:
540 Chemie
Publication Type:
Wissenschaftlicher Artikel
Also published in:
Chem. Commun. - 50 (2014),39, S. 5014-5016
URL of the Original Publication:
DOI of the Original Publication:
Department/institution:
Biologie, Chemie, Pharmazie
