Potential Risk Factors Related to Antimicrobial Usage and Antimicrobial Resistance in Commercial Poultry Production - A Scoping Review

Abstract

Antimicrobial resistance (AMR) constitutes a serious public health issue, and the European Union (EU) requires reduction in the sales of antibiotics in farmed animals of 50% by 2030. A scoping review was conducted in PubMed for the years from 2000 to 2024, limited to the English and German languages, with the aims to (1) provide an overview of factors on commercial poultry farms potentially associated with health-related endpoints such as mortality, disease prevalence, carcass condemnation, performance as well as AMR/antimicrobial usage at different hierarchical levels (animal, flock/batch, stable, farm), and (2) identify inconsistencies with respect to these potential risk factors. Overall, 34 peer-reviewed publications met the inclusion criteria for the review. Significant associations identified in the uni- or multivariable statistical analysis were summarised using graphs and bar charts. The results highlight that risk factor–outcome associations often are complex, inconsistent with regards to the direction of the influence especially for some ordinal or categorical variables. In some associations such as the sex of the animals and performance, contrary directions were reported in different studies—illustrating the multifactorial dynamics of commercial poultry production. This research enhances the understanding of the complexity of commercial poultry production, which is essential when designing future studies and interpreting their results.