dc.contributor.author
Heinrich, Manuel
dc.contributor.author
Zagorscak, Pavle
dc.contributor.author
Bohn, Johannes
dc.contributor.author
Knaevelsrud, Christine
dc.contributor.author
Schulze, Lars
dc.date.accessioned
2025-09-01T06:08:48Z
dc.date.available
2025-09-01T06:08:48Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/49005
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-48728
dc.description.abstract
The ICH E9(R1) Addendum on Estimands and Sensitivity Analysis provides a framework for defining the treatment effect a trial intends to estimate—the estimand. The addendum is widely adopted in pharmaceutical research. However, it remains underutilized in trials investigating internet-based interventions (IBIs). This manuscript introduces the addendum to IBI researchers. It concludes that estimands are essential to improve the interpretability, relevance, and validity of effect estimates derived in IBI trials.
en
dc.format.extent
8 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Outcomes research
en
dc.subject
Clinical trial design
en
dc.subject
internet interventions
en
dc.subject.ddc
100 Philosophie und Psychologie::150 Psychologie::150 Psychologie
dc.title
Using the ICH estimand framework to improve the interpretation of treatment effects in internet interventions
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1038/s41746-025-01936-0
dcterms.bibliographicCitation.journaltitle
npj Digital Medicine
dcterms.bibliographicCitation.url
https://doi.org/10.1038/s41746-025-01936-0
refubium.affiliation
Erziehungswissenschaft und Psychologie
refubium.affiliation.other
Arbeitsbereich Klinisch-Psychologische Intervention
refubium.funding
Springer Nature DEAL
refubium.note.author
Gefördert aus Open-Access-Mitteln der Freien Universität Berlin.
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
2398-6352
