As natural habitats decline and wildlife adapts to increasing anthropogenic disturbance, it is crucial to understand human-wildlife relationships in residential areas. However, relevant studies are limited and mostly focused on single cities. To address this knowledge gap, we investigated people’s preferences for seeing wild mammals in residential areas by conducting and analyzing an online survey distributed across Germany (n = 2997 participants). Our results revealed that preferred species (squirrels, hedgehogs, hares, roe deer) were frequently encountered, whereas unpreferred species were those encountered frequently (rats, martens), as well as those encountered rarely (wild boar, coypus, raccoons). We also found a moderately positive correlation between the number of encounters with mammals and them being preferred by humans. Finally, some socio-demographic variables, particularly gender, garden access, and urbanity, are significantly related to human preferences. Based on our results, we propose tailoring wildlife management in residential areas to promote the positive attributes of preferred wildlife as biodiversity ambassadors, while also addressing ways to mitigate encounters and negative perceptions associated with unpreferred species.