dc.contributor.author
Lampit, Amit
dc.contributor.author
Launder, Nathalie H.
dc.contributor.author
Minkov, Ruth
dc.contributor.author
Rollini, Alice
dc.contributor.author
Davey, Christopher G.
dc.contributor.author
Finke, Carsten
dc.contributor.author
Lautenschlager, Nicola T.
dc.contributor.author
Gavelin, Hanna Malmberg
dc.date.accessioned
2024-03-18T12:05:13Z
dc.date.available
2024-03-18T12:05:13Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/42896
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-42612
dc.description.abstract
Background: People with depression often present with concurrent cognitive impairment. Computerized cognitive training (CCT) is a safe and efficacious strategy to maintain or enhance cognitive performance in a range of clinical populations. However, its efficacy in people with depression and how it varies across populations and design factors are currently unclear.
Methods: We searched MEDLINE, EMBASE, and PsycINFO from inception to 13 July 2021 for randomised controlled trials examining the efficacy of CCT vs any control condition on cognitive, mood, psychiatric symptoms, psychosocial, and daily functioning in adults with depression. Eligible samples include studies specifically targeting people with major depressive disorder as well as those with other diagnoses where at least 50% of the sample meets the clinical criteria for depression, with the exception of major psychiatric disorders or dementia. The primary outcome is change in the overall cognitive performance. Multivariate analyses will be used to examine the effect sizes on each outcome category as well as possible effect modifiers and correlations between categories. The risk of bias will be assessed using the Cochrane risk of bias tool version 2.
Discussion: To the best of our knowledge, this will be the first systematic review and meta-analysis of narrowly defined CCT across clinical populations with depression. We aim to investigate not only whether CCT is efficacious for cognition, but also how such effects vary across design factors, what other clinically relevant outcomes might respond to CCT, and the extent to which they differ across populations.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Major depressive disorder
en
dc.subject
Computerised cognitive training
en
dc.subject
Meta-analysis
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
6
dcterms.bibliographicCitation.doi
10.1186/s13643-021-01872-6
dcterms.bibliographicCitation.journaltitle
Systematic Reviews
dcterms.bibliographicCitation.number
1
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.volume
11
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34991698
dcterms.isPartOf.eissn
2046-4053