dc.contributor.author
Löchel, Jannis
dc.contributor.author
Wassilew, Georgi I.
dc.contributor.author
Krämer, Michael
dc.contributor.author
Kohler, Christopher
dc.contributor.author
Zahn, Robert Karl
dc.contributor.author
Leopold, Vincent Justus
dc.date.accessioned
2023-03-29T10:59:27Z
dc.date.available
2023-03-29T10:59:27Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/38649
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-38365
dc.description.abstract
Background: Administering intraoperative analgesia in patients undergoing periacetabular osteotomy (PAO) is challenging due to both the relevant surgical approach and osteotomies, which are associated with pain. The aim of this study was to assess the effect of the transversus abdominis plane block (TAPb) on intraoperative opioid consumption and circulation parameters in PAO patients.
Patients and Methods: We conducted a two-group randomized-controlled trial involving 42 consecutive patients undergoing PAO for symptomatic developmental dysplasia of the hip (DDH) in our department. Patients assigned to the study group received an ultrasound-guided TAPb with 0.75% ropivacaine before the beginning of the surgery and after general anesthesia induction. Patients assigned to the control group did not receive a TAPb. General anesthesia was conducted according to a defined study protocol. The primary endpoint of the study was the intraoperative opioid consumption, measured in morphine equivalent dose (MED). Secondary endpoints were the assessment of intraoperative heart rate, mean arterial pressure (MAP), need for hypotension treatment, and length of hospital stay (LOHS). A total of 41 patients (n = 21 TAPb group, n = 20 control group) completed the study; of these, 33 were women (88.5%) and 8 were men (19.5%). The mean age at the time of surgery was 28 years (18-43, SD +/- 7.4). All operations were performed by a single high-volume surgeon and all TAPb procedures were performed by a single experienced senior anesthesiologist.
Results: We observed a significantly lower intraoperative opioid consumption in the TAPb group compared to the control group (930 vs. 1186 MED per kg bodyweight; p = 0.016). No significant differences were observed in the secondary outcome parameters. We observed no perioperative complications.
Conclusion: Ultrasound-guided TAPb significantly reduces intraoperative opioid consumption in patients undergoing PAO.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
periacetabular osteotomy
en
dc.subject
pain management
en
dc.subject
intraoperative analgesia
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Transversus Abdominis Plane Block Reduces Intraoperative Opioid Consumption in Patients Undergoing Periacetabular Osteotomy
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
4961
dcterms.bibliographicCitation.doi
10.3390/jcm11174961
dcterms.bibliographicCitation.journaltitle
Journal of Clinical Medicine
dcterms.bibliographicCitation.number
17
dcterms.bibliographicCitation.originalpublishername
MDPI
dcterms.bibliographicCitation.volume
11
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
36078890
dcterms.isPartOf.eissn
2077-0383