dc.contributor.author
Parwani, Abdul Shokor
dc.contributor.author
Jayanata, Adrian
dc.contributor.author
Kraft, Robin
dc.contributor.author
Lacour, Philipp
dc.contributor.author
Blaschke, Florian
dc.contributor.author
Pieske, Burkert
dc.contributor.author
Boldt, Leift-Hendrik
dc.date.accessioned
2023-03-21T14:52:04Z
dc.date.available
2023-03-21T14:52:04Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/38491
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-38209
dc.description.abstract
Background: Contact force (CF)-sensing catheters are commonly used in the field of radiofrequency (RF) ablation to treat atrial fibrillation (AF). Increasing ablation power (e.g., 50 W) has been suggested as a method to reduce procedure times whilst creating safe and lasting lesions.
Methods: We report the first clinical evidence of a 50 W point-by-point RF ablation in 25 consecutive patients with symptomatic AF using a novel CF-sensing catheter with a gold tip (AlCath Force, BIOTRONIK). We collected and analyzed procedural and ablation parameters. The safety and efficacy of the catheter were evaluated.
Results: Altogether, 985 RF lesions in 25 patients were created with a mean number of 39.4 +/- 16.3 lesions per patient. The total skin-to-skin procedure time was 116.1 +/- 35.1 min, and the mean total area dose product was 10.9 +/- 5.1 Gy*cm2. The mean RF time per procedure was 13.2 +/- 6.6 min. The mean RF time per lesion was 20.2 +/- 8.4 s. The mean CF was 15.7 +/- 7.6 g. We observed a mean force time integral of 274.7 +/- 11.1 gs (range: 53 to 496 gs). Acute procedural success, defined as entrance and exit block in all pulmonary veins, could be obtained in all cases. No procedure- or device-related serious adverse events were observed. No audible steam pops occurred. Optical inspection of the catheter after the procedure showed neither charring nor clotting.
Conclusions: We provide the first evidence for the safety and efficacy of 50 W ablation using the AlCath Force gold-tip catheter. These data must be supported by a larger multi-center study.
en
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
contact force sensing
en
dc.subject
atrial fibrillation
en
dc.subject
gold-tip catheter
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
First clinical experience of high-power ablation of atrial fibrillation with a novel contact force-sensing gold-tip catheter
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.5603/cj.a2022.0060
dcterms.bibliographicCitation.journaltitle
Cardiology Journal
dcterms.bibliographicCitation.number
5
dcterms.bibliographicCitation.originalpublishername
Via Medica
dcterms.bibliographicCitation.pagestart
759
dcterms.bibliographicCitation.pageend
765
dcterms.bibliographicCitation.volume
29
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
35762071
dcterms.isPartOf.issn
1897-5593
dcterms.isPartOf.eissn
1898-018X