dc.contributor.author
Armbrust, Robert
dc.contributor.author
Chen, Frank
dc.contributor.author
Richter, Rolf
dc.contributor.author
Muallem, Mustafa Zelal
dc.contributor.author
Mustea, Alexander
dc.contributor.author
Holthaus, Bernd
dc.contributor.author
Sehouli, Jalid
dc.date.accessioned
2023-03-01T12:36:49Z
dc.date.available
2023-03-01T12:36:49Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/38152
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-37865
dc.description.abstract
Minimally invasive surgery (MIS) has become the standard approach in early stage cervical cancer (ECC). However, the recently published "LACC" trial and even others could show inferior PFS and OS of MIS compared to open radical hysterectomy. The results led to a widespread debate about the best surgical approach in ECC. The present survey aimed to get first insights after publication. NOGGO and AGE conducted a nationwide digital survey among 186 Gynecological Cancer Centers. Descriptive statistics and t-tests were performed using SPSS. A majority of the centers were of high expertise and/or experience in treatment of ECC and were highly aware of the LACC trial results. Trial quality and scientific value were rated as very good/good. However, still 40% would not change the standard of care to open surgery. Centers with higher volume and participating in clinical trials were more likely to change. This survey represents insights after the surprising results of recently published trials towards the surgical approach of ECC. There still seems to be a high need of future trials and possible explanations for the unexpected worse outcomes in the MIS group.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
early stage cervical cancer (ECC)
en
dc.subject
Minimally invasive surgery (MIS)
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Results of a German wide survey towards current surgical approach in early stage cervical cancer NOGGO MONITOR 11
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
9774
dcterms.bibliographicCitation.doi
10.1038/s41598-021-89071-0
dcterms.bibliographicCitation.journaltitle
Scientific Reports
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.volume
11
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33963213
dcterms.isPartOf.eissn
2045-2322