dc.contributor.author
Lichterfeld‐Kottner, Andrea
dc.contributor.author
Vogt, Annika
dc.contributor.author
Tomova‐Simitchieva, Tsenka
dc.contributor.author
Blume‐Peytavi, Ulrike
dc.contributor.author
Kottner, Jan
dc.date.accessioned
2022-11-07T13:32:31Z
dc.date.available
2022-11-07T13:32:31Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/36734
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-36447
dc.description.abstract
Pressure ulcers/injuries are caused by sustained loading and deformation of skin and underlying soft tissues. Prophylactic dressings are recommended as an adjunct to other preventive measures such as repositioning and offloading. The aim of this study was to investigate the effects of prophylactic soft silicone multi-layered foam dressings on the skin structure and function of the two most common pressure areas, sacrum and heel, with and without loading. An exploratory randomised cross-over trial using intra-individual comparisons was conducted. Eight healthy volunteers (mean age 27.5 years) were assigned to three groups and either spent 2.5 hours on a standard hospital mattress lying in supine position with and without dressings or spent 2.5 hours with dressings applied but without loading. Skin temperature, stratum corneum, and epidermal hydration increased in all groups irrespective of wearing a dressing and/or loading. Mean roughness decreased at the heels. Reactive hyperaemia and the release of interleukin 1 alpha were associated with loading only. Results suggest that the occlusive effects of dressings are similar or only slightly greater than those observed with non-loading or loading without dressings. Thus, a dressing does not cause additional irritation or skin changes during loading but it may reduce the inflammatory response.
en
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
pressure ulcer
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Effects of loading and prophylactic dressings on the sacral and heel skin: An exploratory cross‐over trial
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1111/iwj.13596
dcterms.bibliographicCitation.journaltitle
International Wound Journal
dcterms.bibliographicCitation.number
6
dcterms.bibliographicCitation.originalpublishername
Wiley
dcterms.bibliographicCitation.pagestart
909
dcterms.bibliographicCitation.pageend
922
dcterms.bibliographicCitation.volume
18
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
DEAL Wiley
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33939289
dcterms.isPartOf.issn
1742-4801
dcterms.isPartOf.eissn
1742-481X