dc.contributor.author
Scheitz, Jan F.
dc.contributor.author
Stengl, Helena
dc.contributor.author
Nolte, Christian H.
dc.contributor.author
Landmesser, Ulf
dc.contributor.author
Endres, Matthias
dc.date.accessioned
2022-10-21T11:34:08Z
dc.date.available
2022-10-21T11:34:08Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/36628
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-36341
dc.description.abstract
Cardiac troponin is a specific and sensitive biomarker to identify and quantify myocardial injury. Myocardial injury is frequently detected after acute ischemic stroke and strongly associated with unfavorable outcomes. Concomitant acute coronary syndrome is only one of several possible differential diagnoses that may cause elevation of cardiac troponin after stroke. As a result, there are uncertainties regarding the correct interpretation and optimal management of stroke patients with myocardial injury in clinical practice. Elevation of cardiac troponin may occur as part of a ‘Stroke-Heart Syndrome’. The term ‘Stroke-Heart Syndrome’ subsumes a clinical spectrum of cardiac complications after stroke including cardiac injury, dysfunction, and arrhythmia which may relate to disturbances of autonomic function and the brain–heart axis. In this review, we provide an up-to-date overview about prognostic implications, mechanisms, and management of elevated cardiac troponin levels in patients with acute ischemic stroke.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Ischemic stroke
en
dc.subject
Cardiac biomarker
en
dc.subject
Stroke-heart-syndrome
en
dc.subject
Cardiac troponin
en
dc.subject
Brain–heart interaction
en
dc.subject
Myocardial injury
en
dc.subject
Myocardial infarction
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Neurological update: use of cardiac troponin in patients with stroke
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s00415-020-10349-w
dcterms.bibliographicCitation.journaltitle
Journal of Neurology
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.pagestart
2284
dcterms.bibliographicCitation.pageend
2292
dcterms.bibliographicCitation.volume
268
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33372247
dcterms.isPartOf.issn
0340-5354
dcterms.isPartOf.eissn
1432-1459