dc.contributor.author
Schilrreff, Priscila
dc.contributor.author
Alexiev, Ulrike
dc.date.accessioned
2022-08-04T12:43:42Z
dc.date.available
2022-08-04T12:43:42Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/35731
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-35446
dc.description.abstract
Chronic inflammation is one of the hallmarks of chronic wounds and is tightly coupled to immune regulation. The dysregulation of the immune system leads to continuing inflammation and impaired wound healing and, subsequently, to chronic skin wounds. In this review, we discuss the role of the immune system, the involvement of inflammatory mediators and reactive oxygen species, the complication of bacterial infections in chronic wound healing, and the still-underexplored potential of natural bioactive compounds in wound treatment. We focus on natural compounds with antioxidant, anti-inflammatory, and antibacterial activities and their mechanisms of action, as well as on recent wound treatments and therapeutic advancements capitalizing on nanotechnology or new biomaterial platforms.
en
dc.format.extent
31 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
chronic wounds
en
dc.subject
inflammation
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::530 Physik::530 Physik
dc.title
Chronic Inflammation in Non-Healing Skin Wounds and Promising Natural Bioactive Compounds Treatment
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
4928
dcterms.bibliographicCitation.doi
10.3390/ijms23094928
dcterms.bibliographicCitation.journaltitle
International Journal of Molecular Sciences
dcterms.bibliographicCitation.number
9
dcterms.bibliographicCitation.originalpublishername
MDPI
dcterms.bibliographicCitation.volume
23
dcterms.bibliographicCitation.url
https://doi.org/10.3390/ijms23094928
refubium.affiliation
Physik
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access