dc.contributor.author
Grune, Jana
dc.contributor.author
Beyhoff, Niklas
dc.contributor.author
Hegemann, Niklas
dc.contributor.author
Lauryn, Jonathan H.
dc.contributor.author
Kuebler, Wolfgang M.
dc.date.accessioned
2022-07-22T13:20:14Z
dc.date.available
2022-07-22T13:20:14Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/35647
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-35361
dc.description.abstract
Traditionally, the lung has been excluded from the ultrasound organ repertoire and, hence, the application of lung ultrasound (LUS) was largely limited to a few enthusiastic clinicians. Yet, in the last decades, the recognition of the previously untapped diagnostic potential of LUS in intensive care medicine has fueled its widespread use as a rapid, non-invasive and radiation-free bedside approach with excellent diagnostic accuracy for many of the most common causes of acute respiratory failure, e.g., cardiogenic pulmonary edema, pneumonia, pleural effusion and pneumothorax. Its increased clinical use has also incited attention for the potential usefulness of LUS in preclinical studies with small animal models mimicking lung congestion and pulmonary edema formation. Application of LUS to small animal models of pulmonary edema may save time, is cost-effective, and may reduce the number of experimental animals due to the possibility of serial evaluations in the same animal as compared with traditional end-point measurements. This review provides an overview of the emerging field of LUS with a specific focus on its application in animal models and highlights future perspectives for LUS in preclinical research.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Animal models
en
dc.subject
Lung ultrasound
en
dc.subject
Pulmonary edema
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
From bedside to bench: lung ultrasound for the assessment of pulmonary edema in animal models
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s00441-020-03172-2
dcterms.bibliographicCitation.journaltitle
Cell and Tissue Research
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.pagestart
379
dcterms.bibliographicCitation.pageend
392
dcterms.bibliographicCitation.volume
380
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32009189
dcterms.isPartOf.issn
0302-766X
dcterms.isPartOf.eissn
1432-0878