dc.contributor.author
Schleusener, Johannes
dc.contributor.author
Schanzer, Sabine
dc.contributor.author
Wille, Charlotte
dc.contributor.author
Langen, Valentin
dc.contributor.author
Richter, Heike
dc.contributor.author
Lademann, Jürgen
dc.contributor.author
Meinke, Martina C.
dc.date.accessioned
2022-04-25T13:18:19Z
dc.date.available
2022-04-25T13:18:19Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/34835
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-34554
dc.description.abstract
Background: The recommended amount of sunscreen by hand application (2 mg/cm(2)) is in reality not achieved, which decreases the homogeneity and thereby the effective sun protection factor (SPF).
Materials and Methods: The homogeneity of sunscreen applied by a newly developed spray applicator using an electrostatically charged aerosol, for which a hand rubbing of the formulation is not necessary, is evaluated. In vivo experiments were performed on the volar forearms of human volunteers using the spray applicator compared to the standardized hand application according to ISO 24444.
Results: The distribution homogeneity was assessed qualitatively using in vivo laser scanning microscopy and quantitatively by absorption spectroscopy after tape stripping and by the standard deviation of multiple spatially displaced reflectance measurements for non-invasive SPF determination below the minimal erythemal dose, which showed a significantly higher homogeneity by 20.9% after spray application compared to hand application.
Conclusion: Non-invasive SPF determination of multiple spatially displaced reflectance measurements was proven to be a suitable method for the non-invasive determination of the sunscreen distribution homogeneity. Electrostatically charged spray application increased the sunscreen distribution homogeneity on the skin and can reduce the amount of overspray.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
confocal laser scanning microscopy
en
dc.subject
spectroscopy
en
dc.subject
sun protection factor
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Electrohydrodynamic spray applicator for homogenous application and reduced overspray of sunscreen
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1111/srt.12924
dcterms.bibliographicCitation.journaltitle
Skin Research and Technology
dcterms.bibliographicCitation.number
2
dcterms.bibliographicCitation.originalpublishername
Wiley
dcterms.bibliographicCitation.pagestart
191
dcterms.bibliographicCitation.pageend
200
dcterms.bibliographicCitation.volume
27
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
DEAL Wiley
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32686864
dcterms.isPartOf.issn
0909-752X
dcterms.isPartOf.eissn
1600-0846