dc.contributor.author
Varchmin, Leonie
dc.contributor.author
Montag, Christiane
dc.contributor.author
Treusch, Yvonne
dc.contributor.author
Kaminski, Jakob
dc.contributor.author
Heinz, Andreas
dc.date.accessioned
2022-02-22T08:29:35Z
dc.date.available
2022-02-22T08:29:35Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/34087
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-33805
dc.description.abstract
Exposure to childhood trauma is a well-known risk factor for severe mental disorders including schizophrenia and other non-affective psychoses. Beyond childhood trauma, there is increasing evidence that bullying, social exclusion, and discrimination during adolescence and adulthood may increase the risk of developing a psychotic disorder, and that such forms of traumatization may also underlie the elevated psychosis risk among migrants or persons with a visible minority status. In this umbrella review, we systematically assess meta-analyses regarding trauma and social adversity. A systematic literature review yielded 11 meta-analyses that met inclusion criteria and could be summarized quantitatively with a random effect model. Furthermore, six meta-analyses were evaluated qualitatively. Heterogeneity and publication bias were apparent in several meta-analyses. We observed that most significant social risk factors for psychosis were vulnerability for racist discrimination [OR = 3.90 (3.25-4.70)], migration [OR = 2.22 (1.75-2.80)], and childhood adversities [OR = 2.81 (2.03-3.83)]. Furthermore, social factors increasing the risk for psychosis were variation/impairment of parental communication, aversive adult life events, bullying, and factors associated with social isolation and discrimination. In spite of these environmental risk factors, there is a lack of evidence regarding treatment of trauma and psychosis, although some psychotherapeutic and art therapy approaches appear to be promising. Beyond individual interventions, stigmatization, racism, and other forms of discrimination need to be targeted to increase solidarity and communal support.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
umbrella review
en
dc.subject
meta-analysis
en
dc.subject
discrimination
en
dc.subject
schizophrenia
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Traumatic Events, Social Adversity and Discrimination as Risk Factors for Psychosis - An Umbrella Review
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
665957
dcterms.bibliographicCitation.doi
10.3389/fpsyt.2021.665957
dcterms.bibliographicCitation.journaltitle
Frontiers in Psychiatry
dcterms.bibliographicCitation.originalpublishername
Frontiers Media SA
dcterms.bibliographicCitation.volume
12
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34744806
dcterms.isPartOf.eissn
1664-0640