dc.contributor.author
Eggert, Torsten
dc.contributor.author
Dorn, Hans
dc.contributor.author
Danker-Hopfe, Heidi
dc.date.accessioned
2022-01-27T12:25:02Z
dc.date.available
2022-01-27T12:25:02Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/33733
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-33453
dc.description.abstract
Purpose: Quantification of nocturnal EEG activity has emerged as a promising extension to the conventional sleep evaluation approach. To date, studies focusing on quantitative sleep EEG data in relation to age and sex have revealed considerable variation across lifespan and differences between men and women. However, sleep EEG power values from elderly individuals are still rare. The present secondary analysis aimed to fill this gap.
Participants and Methods: Sleep EEG data of 30 healthy elderly males (mean age +/- SD: 69.1 +/- 5.5 years), 30 healthy elderly females (67.8 +/- 5.7 years), and of 30 healthy young males (25.6 +/- 2.4 years) have been collected in three different studies with the same experimental design. Each individual contributed three polysomnographic recordings without any intervention to the analysis. Sleep recordings were performed and evaluated according to the standard of the American Academy of Sleep Medicine. Sleep EEG signals were derived from 19 electrode sites. Sleep-stage specific global and regional EEG power were compared between samples using a permutation-based statistic in combination with the threshold-free cluster enhancement method.
Results: The present results showed pronounced differences in sleep EEG power between older men and women. The nocturnal EEG activity of older women was generally larger than that of older men, confirming previously reported variations with sex in younger individuals. Aging was reflected by differences in EEG power between young and elderly men for lower frequencies and for the sleep spindle frequency range, again consistent with prior studies.
Conclusion: The findings of this investigation complement those of earlier studies. They add to the understanding of nocturnal brain activity manifestation in senior adulthood and show how it differs with age in males. Unfortunately, the lack of information on young women prevents a similar insight for females.
en
dc.rights.uri
https://creativecommons.org/licenses/by-nc/3.0/
dc.subject
neurophysiology
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Nocturnal Brain Activity Differs with Age and Sex: Comparisons of Sleep EEG Power Spectra Between Young and Elderly Men, and Between 60–80-Year-Old Men and Women
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.2147/nss.s327221
dcterms.bibliographicCitation.journaltitle
Nature and Science of Sleep
dcterms.bibliographicCitation.originalpublishername
Dove Medical Press
dcterms.bibliographicCitation.pagestart
1611
dcterms.bibliographicCitation.pageend
1630
dcterms.bibliographicCitation.volume
13
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34584476
dcterms.isPartOf.eissn
1179-1608