Haupttitel:
Spatial working memory performance in people with obsessive–compulsive disorder, their unaffected first-degree relatives and healthy controls
Verfasser*in:
Heinzel, Stephan; Bey, Katharina; Grützmann, Rosa; Klawohn, Julia; Kaufmann, Christian; Lennertz, Leonhard; Wagner, Michael; Kathmann, Norbert; Riesel, Anja
Datum der Freigabe:
2021-12-13T14:26:02Z
Abstract:
Studies have shown that people with obsessive–compulsive disorder (OCD) have impairments in spatial working memory (SWM) performance. However, it remains unclear whether this deficit represents a cognitive endophenotype preceding symptoms or a correlate of OCD. We investigated SWM in 69 people with OCD, 77 unaffected first-degree relatives of people with OCD and 106 healthy control participants. Taking age effects into account, SWM performance was best in healthy controls, intermediate in relatives and worst in OCD participants. However, since performance did not differ significantly between healthy controls and relatives, our study does not fully support SWM performance as a core cognitive endophenotype of OCD.
Teil des Identifiers:
e-ISSN (online): 2056-4724
Freie Schlagwörter:
Obsessive–compulsive disorder
spatial working memory
endophenotype
first-degree relatives
DDC-Klassifikation:
150 Psychologie
Publikationstyp:
Wissenschaftlicher Artikel
Zeitschrift:
BJPsych Open
Fachbereich/Einrichtung:
Erziehungswissenschaft und Psychologie
Arbeitsbereich Klinische Psychologie und Psychotherapie
Anmerkungen:
Die Publikation wurde aus Open Access Publikationsgeldern der Freien Universität Berlin gefördert.