dc.contributor.author
Janke, David
dc.contributor.author
Kagelmann, Niklas
dc.contributor.author
Storm, Christian
dc.contributor.author
Maggioni, Martina A.
dc.contributor.author
Kienast, Camilla
dc.contributor.author
Gunga, Hanns-Christian
dc.contributor.author
Opatz, Oliver
dc.date.accessioned
2021-09-28T09:18:07Z
dc.date.available
2021-09-28T09:18:07Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/32083
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-31811
dc.description.abstract
Background: Precisely measuring the core body temperature during targeted temperature management after return of spontaneous circulation is mandatory, as deviations from the recommended temperature might result in side effects such as electrolyte imbalances or infections. However, previous methods are invasive and lack easy handling. A disposable, non-invasive temperature sensor using the heat flux approach (Double Sensor), was tested against the standard method: an esophagus thermometer.
Methods: The sensor was placed on the forehead of adult patients (n = 25, M/F, median age 61 years) with return of spontaneous circulation after cardiac arrest undergoing targeted temperature management. The recorded temperatures were compared to the established measurement method of an esophageal thermometer. A paired t-test was performed to examine differences between methods. A Bland-Altman-Plot and the intraclass correlation coefficient were used to assess agreement and reliability. To rule out possible influence on measurements, the patients' medication was recorded as well.
Results: Over the span of 1 year and 3 months, data from 25 patients were recorded. The t-test showed no significant difference between the two measuring methods (t = 1.47, p = 0.14, n = 1,319). Bland-Altman results showed a mean bias of 0.02 degrees C (95% confidence interval 0.00-0.04) and 95% limits of agreement of -1.023 degrees C and 1.066 degrees C. The intraclass correlation coefficient was 0.94. No skin irritation or allergic reaction was observed where the sensor was placed. In six patients the bias differed noticeably from the rest of the participants, but no sex-based or ethnicity-based differences could be identified. Influences on the measurements of the Double Sensor by drugs administered could also be ruled out.
Conclusions: This study could demonstrate that measuring the core body temperature with the non-invasive, disposable sensor shows excellent reliability during targeted temperature management after survived cardiac arrest. Nonetheless, clinical research concerning the implementation of the sensor in other fields of application should be supported, as well as verifying our results by a larger patient cohort to possibly improve the limits of agreement.
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dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
core body temperature
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dc.subject
return of spontaneous circulation
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dc.subject
targeted temperature management
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dc.subject
cardiac arrest
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dc.subject
intraclass correlation coefficient
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dc.subject
heat-flux sensor
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Measuring Core Body Temperature Using a Non-invasive, Disposable Double-Sensor During Targeted Temperature Management in Post-cardiac Arrest Patients
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
666908
dcterms.bibliographicCitation.doi
10.3389/fmed.2021.666908
dcterms.bibliographicCitation.journaltitle
Frontiers in Medicine
dcterms.bibliographicCitation.originalpublishername
Frontiers Media SA
dcterms.bibliographicCitation.volume
8
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34026794
dcterms.isPartOf.eissn
2296-858X