dc.contributor.author
Sabbavarapu, Narayana Murthy
dc.contributor.author
Seeberger, Peter H.
dc.date.accessioned
2021-08-30T11:29:49Z
dc.date.available
2021-08-30T11:29:49Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/31765
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-31497
dc.description.abstract
Galactofurans are an important structural constituent of arabinogalactan and lipopolysaccharides (LPS) ubiquitously present on the envelopes of all Mycobacteria. Key to the automated glycan assembly (AGA) of linear galactofuranosides as long as 20-mers was the identification of thioglycoside building blocks with a fine balance of stereoelectronic and steric effects to ensure the stability of oligogalactofuranoside during the synthesis. A benzoylated galactofuranose thioglycoside building block proved most efficient for oligosaccharide construction.
en
dc.format.extent
8 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Column chromatography
en
dc.subject
Organic polymers
en
dc.subject
Ethyl groups
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
dc.title
Automated Glycan Assembly of Oligogalactofuranosides Reveals the Influence of Protecting Groups on Oligosaccharide Stability
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1021/acs.joc.1c00505
dcterms.bibliographicCitation.journaltitle
Journal of Organic Chemistry
dcterms.bibliographicCitation.number
10
dcterms.bibliographicCitation.pagestart
7280
dcterms.bibliographicCitation.pageend
7287
dcterms.bibliographicCitation.volume
86
dcterms.bibliographicCitation.url
https://doi.org/10.1021/acs.joc.1c00505
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Chemie und Biochemie
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
1520-6904
refubium.resourceType.provider
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