dc.contributor.author
Pohlmann, Dominika
dc.contributor.author
Barth, Anne
dc.contributor.author
Macedo, Sergio
dc.contributor.author
Pleyer, Uwe
dc.contributor.author
Winterhalter, Sibylle
dc.contributor.author
Albayrak, Özgür
dc.date.accessioned
2021-04-27T06:30:19Z
dc.date.available
2021-04-27T06:30:19Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/30551
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-30291
dc.description.abstract
To evaluate the impact of Birdshot-Retinochoroidopathy (BSRC) and Serpiginous Choroiditis (SC) on depression, anxiety, and vision-related quality of life. 72 individuals (BSRC: n = 28, SC: n = 8; healthy control group (HC): n = 36) completed the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and the Visual Function Questionnaire (VFQ-25). Multivariate linear regression models were used to analyze different subscales of the PHQ-9, the GAD-7 and the VFQ-25. The results showed that the mean of PHQ-9 was significantly higher while the mean of the VFQ-25 and its ' subscales were consistently lower in the disease group compared to HC. The mean of GAD-7 was not significantly lower in the disease group compared to HC. Stratification for different disease severity stages and duration of disease did not reveal any differences in sum scores of PHQ-9, GAD-7, and VFQ-25, whereas there were significant differences in some subscales of the VFQ-25. We conclude that BSRC and SC patients show higher levels of depression and a reduced visual quality of life due to imminent loss of vision. Because depression and quality of life are adversely affected by lack of social contacts and functioning, psychological treatment should enable patients to maintain their independence and ability to social interaction. Psychosomatic care should be taken in account for the treatment of BSRC and SC.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Anxiety Disorders
en
dc.subject
Birdshot Chorioretinopathy
en
dc.subject
Severity of Illness Index
en
dc.subject
Sickness Impact Profile
en
dc.subject
White Dot Syndromes
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
The impact of impending / onset of vision loss on depression, anxiety, and vision-related quality of life in Birdshot-Retinochoroiditis and Serpiginous Choroiditis
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
e0239210
dcterms.bibliographicCitation.doi
10.1371/journal.pone.0239210
dcterms.bibliographicCitation.journaltitle
PLOS ONE
dcterms.bibliographicCitation.number
10
dcterms.bibliographicCitation.originalpublishername
Public Library of Science (PLoS)
dcterms.bibliographicCitation.volume
15
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33017403
dcterms.isPartOf.eissn
1932-6203