dc.contributor.author
Karavaev, Anatoly S.
dc.contributor.author
Ishbulatov, Yurii M.
dc.contributor.author
Prokhorov, Mikhail D.
dc.contributor.author
Ponomarenko, Vladimir I.
dc.contributor.author
Kiselev, Anton R.
dc.contributor.author
Runnova, Anastasiia E.
dc.contributor.author
Hramkov, Alexey N.
dc.contributor.author
Semyachkina-Glushkovskaya, Oxana V.
dc.contributor.author
Kurths, Jürgen
dc.contributor.author
Penzel, Thomas
dc.date.accessioned
2021-03-01T15:49:16Z
dc.date.available
2021-03-01T15:49:16Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/29783
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-29525
dc.description.abstract
We propose a mathematical model of the human cardiovascular system. The model allows one to simulate the main heart rate, its variability under the influence of the autonomic nervous system, breathing process, and oscillations of blood pressure. For the first time, the model takes into account the activity of the cerebral cortex structures that modulate the autonomic control loops of blood circulation in the awake state and in various stages of sleep. The adequacy of the model is demonstrated by comparing its time series with experimental records of healthy subjects in the SIESTA database. The proposed model can become a useful tool for studying the characteristics of the cardiovascular system dynamics during sleep.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
autonomic control
en
dc.subject
cardio-vascular system
en
dc.subject
mathematical modeling
en
dc.subject
non-linear dynamics
en
dc.subject
sleep studies
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Simulating Dynamics of Circulation in the Awake State and Different Stages of Sleep Using Non-autonomous Mathematical Model With Time Delay
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
612787
dcterms.bibliographicCitation.doi
10.3389/fphys.2020.612787
dcterms.bibliographicCitation.journaltitle
Frontiers in Physiology
dcterms.bibliographicCitation.originalpublishername
Frontiers Media SA
dcterms.bibliographicCitation.volume
11
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33519518
dcterms.isPartOf.eissn
1664-042X