dc.contributor.author
Kooshkaki, Omid
dc.contributor.author
Derakhshani, Afshin
dc.contributor.author
Conradie, Andelé M.
dc.contributor.author
Hemmat, Nima
dc.contributor.author
Barreto, Savio George
dc.contributor.author
Baghbanzadeh, Amir
dc.contributor.author
Singh, Pankaj Kumar
dc.contributor.author
Safarpour, Hossein
dc.contributor.author
Asadzadeh, Zahra
dc.contributor.author
Najafi, Souzan
dc.date.accessioned
2021-01-13T09:58:10Z
dc.date.available
2021-01-13T09:58:10Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/29244
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28991
dc.description.abstract
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease 2019 (COVID-19) in China, which spread to the rest of the world, led the World Health Organization to classify it as a global pandemic. COVID-19 belongs to the Bettacoronavirus genus of the Coronaviridae family, and it mainly spreads through the respiratory tract. Studies have now confirmed a human-to-human transmission as the primary pathway of spread. COVID-19 patients with a history of diseases such as respiratory system diseases, immune deficiency, diabetes, cardiovascular disease, and cancer are prone to adverse events (admission to the intensive care unit requiring invasive ventilation or even death). The current focus has been on the development of novel therapeutics, including antivirals, monoclonal antibodies, and vaccines. However, although there is undoubtedly an urgent need to identify effective treatment options against infection with COVID-19, it is equally important to clarify management protocols for the other significant diseases from which these patients may suffer, including cancer. This review summarizes the current evidence regarding the epidemiology, pathogenesis, and management of patients with COVID-19. It also aims to provide the reader with insights into COVID-19 in pregnant patients and those with cancer, outlining necessary precautions relevant to cancer patients. Finally, we provide the available evidence on the latest potent antiviral drugs and vaccines of COVID-19 and the ongoing drug trials.
en
dc.format.extent
17 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
coronavirus disease 2019
en
dc.subject
coronavirus disease
en
dc.subject
severe acute respiratory syndrome coronavirus 2
en
dc.subject
severe acute respiratory syndrome
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie
dc.title
Coronavirus Disease 2019: A Brief Review of the Clinical Manifestations and Pathogenesis to the Novel Management Approaches and Treatments
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
572329
dcterms.bibliographicCitation.doi
10.3389/fonc.2020.572329
dcterms.bibliographicCitation.journaltitle
Frontiers in Oncology
dcterms.bibliographicCitation.volume
10
dcterms.bibliographicCitation.url
https://doi.org/10.3389/fonc.2020.572329
refubium.affiliation
Veterinärmedizin
refubium.affiliation.other
Institut für Virologie

refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
2234-943X
refubium.resourceType.provider
WoS-Alert