dc.contributor.author
Kulka, Michaël W.
dc.contributor.author
Nie, Chuanxiong
dc.contributor.author
Nickl, Philip
dc.contributor.author
Kerkhoff, Yannic
dc.contributor.author
Garg, Arushi
dc.contributor.author
Salz, Dirk
dc.contributor.author
Radnik, Jörg
dc.contributor.author
Grunwald, Ingo
dc.contributor.author
Haag, Rainer
dc.date.accessioned
2021-01-11T11:44:03Z
dc.date.available
2021-01-11T11:44:03Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/29212
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28960
dc.description.abstract
Biofouling is a major challenge in the application of textiles, biosensors, and biomedical implants. In the current work, a straightforward method for the solvent-free polymerization of antifouling dendritic polyglycerol (dPG) from mussel-inspired dendritic polyglycerol (MI-dPG) coatings on hydrophilic titanium dioxide (TiO2) and hydrophobic polydimethylsiloxane (PDMS) is reported. Surface characterization is performed by static water contact angle (CA) measurements, X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). Significant lower CA values are obtained after dPG grafting from MI-dPG-coated TiO2 and MI-dPG coated PDMS. Furthermore, XPS shows a time-dependent increase of the C-O bond content upon dPG grafting from MI-dPG-coated TiO2 and MI-dPG-coated PDMS. Analysis of the surface morphology by SEM shows a clear time-dependent increase in the surface roughness upon dPG grafting from MI-dPG-coated TiO2 and MI-dPG-coated PDMS. When the viability of two adhesive cell types is studied via LIVE/DEAD staining, a strong reduction in the cell density is observed after the dPG grafting from MI-dPG-coated TiO2 and MI-dPG-coated PDMS (a decrease of >95% in all cases). The combined results show that biocompatible but highly cell-repelling surfaces are efficiently constructed via the grafting of dPG from MI-dPG-coated TiO2 and MI-dPG-coated PDMS.
de
dc.format.extent
11 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
cell-repelling surface coatings
en
dc.subject
dendritic polyglycerol
en
dc.subject
mussel-inspired adhesives
en
dc.subject
surface-initiated grafting
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::540 Chemie::547 Organische Chemie
dc.title
Surface-Initiated Grafting of Dendritic Polyglycerol from Mussel-Inspired Adhesion-Layers for the Creation of Cell-Repelling Coatings
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
2000931
dcterms.bibliographicCitation.doi
10.1002/admi.202000931
dcterms.bibliographicCitation.journaltitle
Advanced Materials Interfaces
dcterms.bibliographicCitation.number
24
dcterms.bibliographicCitation.volume
7
dcterms.bibliographicCitation.url
https://doi.org/10.1002/admi.202000931
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Chemie und Biochemie

refubium.funding
DEAL Wiley
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
2196-7350
refubium.resourceType.provider
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