dc.contributor.author
Longardt, Ann Carolin
dc.contributor.author
Loui, Andrea
dc.contributor.author
Bührer, Christoph
dc.contributor.author
Berns, Monika
dc.date.accessioned
2020-10-16T07:19:20Z
dc.date.available
2020-10-16T07:19:20Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/28540
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28289
dc.description.abstract
Background: Milk curd obstruction as a cause of intestinal obstruction has been known since 1959, but has nearly disappeared. However, in recent years it has experienced a revival in small premature infants. Objective: The aim of this study was to evaluate the clinical characteristics of milk curd obstruction (lactobezoar) in preterm infants. Methods: Data of preterm infants with milk curd obstruction cared for at a large tertiary neonatal intensive care unit between 2012 and 2016 were retrieved from the electronic registry and paper records. Results: A total of 10 infants (2 girls, 8 boys) were identified: the median birth weight was 595 g (range 270-922), gestational age was 24.4 weeks (23.4-27.0), weight-for-gestational age percentile was 16 (0-62), and age at diagnosis was 28 days (16-64). Five infants (50%) were small for gestational age. All neonates had received fortified human milk (added protein 2.0 g/100 mL, range 0-2.8; added calcium 2,400 μmol/100 mL, range 0-6 844; added phosphate 2,400 μmol/100 mL, range 0-5,178). Seven neonates underwent surgery, and 2 infants died. Hyperechoic masses in extended bowel loops, visualised by abdominal ultrasound, and pale/acholic faeces were hallmarks of milk curd obstruction. Conclusions: In this study, milk curd obstruction occurred exclusively in infants with a birth weight < 1,000 g (2.2%) and <28 weeks' gestational age (2.4%). Male and small for gestational age infants appeared to be at increased risk. Paying attention to the colour of the faeces of infants at risk might help to diagnose milk curd obstruction at an early stage.
en
dc.subject
Milk curd obstruction
en
dc.subject
Intestinal obstruction
en
dc.subject
Fortified breast milk
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Milk Curd Obstruction in Human Milk-Fed Preterm Infants
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1159/000494625
dcterms.bibliographicCitation.journaltitle
Neonatology
dcterms.bibliographicCitation.number
3
dcterms.bibliographicCitation.originalpublishername
Karger
dcterms.bibliographicCitation.pagestart
211
dcterms.bibliographicCitation.pageend
216
dcterms.bibliographicCitation.volume
115
dcterms.rightsHolder.note
Copyright applies in this work.
dcterms.rightsHolder.url
http://rightsstatements.org/vocab/InC/1.0/
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.note.author
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
de
refubium.note.author
This publication is shared with permission of the rights owner and made freely accessible through a DFG (German Research Foundation) funded license at either an alliance or national level.
en
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
30646004
dcterms.isPartOf.issn
1661-7800
dcterms.isPartOf.eissn
1661-7819