dc.contributor.author
Berlin, Max
dc.contributor.author
Kupsch, Christiane
dc.contributor.author
Ritter, Lea
dc.contributor.author
Stoelcker, Benjamin
dc.contributor.author
Heusinger, Anton
dc.contributor.author
Gräser, Yvonne
dc.date.accessioned
2020-10-14T13:34:13Z
dc.date.available
2020-10-14T13:34:13Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/28517
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28266
dc.description.abstract
For about 10 years, a new variant of the pathogen Trichophyton (T.) benhamiae has appeared in Germany, characterized by a previously unobserved culture phenotype with a strong yellow reverse. A few studies suggest that this new variety is now the most common zoophilic dermatophyte in Germany. The guinea pig is the main carrier. Exact prevalence measurements are not yet available. Thus, the aim of our ongoing study was to collect data on the frequency and geographic distribution of the pathogen and its phenotypes (white and yellow) in humans and guinea pigs throughout Germany. Our former studies have already shown that animals from large breeding farms are particularly heavily affected. In contrast to this, 21 small, private breedings were sampled and husbandry conditions recorded. This placed us in a position to identify propagation factors and to give recommendations for containment. For animals from private breedings, we detected T. benhamiae with a prevalence of 55.4%, which is a reduction of nearly 40% compared with animals from large breeding farms. As risk factors, we identified the type of husbandry and the contact to other breedings. Furthermore, certain animal races, like Rex guinea pigs and races with long hair in combination with curls were predestined for colonization with T. benhamiae due to their phenotypic coat characteristics. A prevalence for infections with T. benhamiae of 36.2% has been determined for symptomatic pet guinea pigs suspected of having dermatophytosis and is comparable to the study of Kraemer et al. showing a prevalence of 34.9% in 2009 in Germany. The prevalence in humans is stable with about 2-3% comparing the data of 2010-2013 and 2018 in Thuringia. The new type of T. benhamiae was by far the most frequent cause in all settings.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
dermatophyte
en
dc.subject
Trichophyton benhamiae
en
dc.subject
epidemiology
en
dc.subject
emerging pathogen
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
German-Wide Analysis of the Prevalence and the Propagation Factors of the Zoonotic Dermatophyte Trichophyton benhamiae
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
0161
dcterms.bibliographicCitation.doi
10.3390/jof6030161
dcterms.bibliographicCitation.journaltitle
Journal of Fungi
dcterms.bibliographicCitation.originalpublishername
MDPI AG
dcterms.bibliographicCitation.volume
6
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32899171
dcterms.isPartOf.eissn
2309-608X