dc.contributor.author
Macedo, Sergio
dc.contributor.author
Pohlmann, Dominika
dc.contributor.author
Lenglinger, Matthias
dc.contributor.author
Pleyer, Uwe
dc.contributor.author
Jousson, Antonia M.
dc.contributor.author
Winterhalter, Sibylle
dc.date.accessioned
2020-10-20T10:35:45Z
dc.date.available
2020-10-20T10:35:45Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/28374
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28124
dc.description.abstract
Background:
To describe changes in the retina/choroid in patients with Serpiginous Choroiditis (SC) by Optical Coherence Tomography Angiography (OCTA) in a multimodal imaging approach.
Methods:
Prospective, monocentric study of 24 eyes of 12 consenting patients diagnosed with SC, who underwent OCTA, which was analyzed and compared to other methods such as enhanced depth imaging-OCT, fluorescein angiography, indocyanine green angiography, and fundus autofluorescence.
Results:
The study group consisted of 9 patients with peripapillary SC, 1 macular SC, and 2 atypical cases. All eyes presented an inactive SC confirmed by standard imaging. OCTA demonstrated the lesions tridimensionally in great detail. There was no difference in the angioarchitecture among the 3 forms of SC. A loss of the choriocapillaris/retinal pigment epithelium left a “window-defect”, where the vessels of larger caliber of the choroid became recognizable and their appearance inverted (“white-on-black”). A relationship between the presence of segmentation errors (SE) in the slabs and low visual acuity was established with a one-way ANOVA.
Conclusions:
OCTA was able to non-invasively assess vascular lesions of the choroid/retina in patients with SC with a high degree of correlation to other diagnostic modalities. Consequent long-term assessments could lead to a better understanding of disease progression.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Fluorescein angiography
en
dc.subject
Fundus autofluorescence
en
dc.subject
Indocyanin green angiography
en
dc.subject
Optical coherence tomography angiography
en
dc.subject
Posterior uveitis
en
dc.subject
Serpiginous Choroiditis
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Optical coherence tomography angiography (OCTA) findings in Serpiginous Choroiditis
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
258
dcterms.bibliographicCitation.doi
10.1186/s12886-020-01527-5
dcterms.bibliographicCitation.journaltitle
BMC Ophthalmology
dcterms.bibliographicCitation.originalpublishername
BMC
dcterms.bibliographicCitation.volume
20
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32605555
dcterms.isPartOf.eissn
1471-2415