dc.contributor.author
Miszczuk, Milena
dc.contributor.author
Müller, Verena
dc.contributor.author
Althoff, Christian E.
dc.contributor.author
Stroux, Andrea
dc.contributor.author
Widhalm, Daniela
dc.contributor.author
Dobberstein, Andy
dc.contributor.author
Greiner, Andreas
dc.contributor.author
Kuivaniemi, Helena
dc.contributor.author
Hinterseher, Irene
dc.date.accessioned
2020-09-17T09:15:33Z
dc.date.available
2020-09-17T09:15:33Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/28218
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-27968
dc.description.abstract
Background:
Abdominal aortic aneurysms (AAA) primarily affect men over 65 years old who often have many other diseases, with similar risk factors and pathobiological mechanisms to AAA. The aim of this study was to assess the prevalence of simple renal cysts (SRC), chronic kidney disease (CKD), and other kidney diseases (e.g. nephrolithiasis) among patients presenting with AAA.
Methods:
Two groups of patients (97 AAA and 100 controls), with and without AAA, from the Surgical Clinic Charité, Berlin, Germany, were selected for the study. The control group consisted of patients who were evaluated for a kidney donation (n = 14) and patients who were evaluated for an early detection of a melanoma recurrence (n = 86). The AAA and control groups were matched for age and sex. Medical records were analyzed and computed tomography scans were reviewed for the presence of SRC and nephrolithiasis.
Results:
SRC (74% vs. 57%; p<0.016) and CKD (30% vs. 8%; p<0.001) were both more common among AAA than control group patients. On multivariate analysis, CKD, but not SRC, showed a strong association with AAA.
Conclusions:
Knowledge about pathobiological mechanisms and association between CKD and AAA could provide better diagnostic and therapeutic approaches for these patients.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
abdominal aortic aneurysm
en
dc.subject
chronic kidney disease
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
201
dcterms.bibliographicCitation.doi
10.1186/s12882-020-01841-6
dcterms.bibliographicCitation.journaltitle
BMC Nephrology
dcterms.bibliographicCitation.originalpublishername
BMC
dcterms.bibliographicCitation.volume
21
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
32471416
dcterms.isPartOf.eissn
1471-2369