dc.contributor.author
Spielmann, Horst
dc.date.accessioned
2019-12-12T11:28:18Z
dc.date.available
2019-12-12T11:28:18Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/26117
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-25877
dc.description.abstract
We reviewed six key peer-reviewed publications that assessed the need for one-year studies of pesticide toxicity in dogs. Each of the six papers took a different approach to comparing the value of one-year studies relative to three-month studies, and despite the adoption of different databases and approaches, each study reached the same conclusion: the recommended limit to the testing of pesticide toxicity in dogs should be three months.
Therefore, the present review supports the conclusion that the routine inclusion of a one-year dog study should not be a mandatory requirement for the safety assessment of pesticides, since it is scientifically no longer justifiable. We recommend that the OECD should adapt a harmonized approach that is in line with the legislation in Europe and the USA.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Safety testing of pesticides
en
dc.subject
Regulatory testing
en
dc.subject
Length of studies
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik
dc.title
Progress in Eliminating One-Year Dog Studies for the Safety Assessment of Pesticides
dcterms.bibliographicCitation.booktitle
Alternatives to Animal Testing
dcterms.bibliographicCitation.doi
10.1007/978-981-13-2447-5_6
dcterms.bibliographicCitation.originalpublishername
Springer Open
dcterms.bibliographicCitation.originalpublisherplace
Schweiz
dcterms.bibliographicCitation.pagestart
50
dcterms.bibliographicCitation.pageend
56
dcterms.bibliographicCitation.url
https://doi.org/10.1007/978-981-13-2447-5_6
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Pharmazie
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.isbn
978-981-13-2446-8
dcterms.isPartOf.eisbn
978-981-13-2447-5
