dc.contributor.author
Koch, Susanne
dc.contributor.author
Stegherr, Anna-Maria
dc.contributor.author
Rupp, Leopold
dc.contributor.author
Kruppa, Jochen
dc.contributor.author
Prager, Christine
dc.contributor.author
Kramer, Sylvia
dc.contributor.author
Fahlenkamp, Astrid
dc.contributor.author
Spies, Claudia
dc.date.accessioned
2019-11-22T13:06:11Z
dc.date.available
2019-11-22T13:06:11Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/25977
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-25734
dc.description.abstract
BACKGROUND:
Emergence-delirium is the most frequent brain dysfunction in children recovering from general anaesthesia, though the pathophysiological background remains unclear. The presented study analysed an association between emergence delirium and intraoperative Burst Suppression activity in the electroencephalogram, a period of very deep hypnosis during general anaesthesia.
METHODS:
In this prospective, observational cohort study at the Charité - university hospital in Berlin / Germany children aged 0.5 to 8 years, undergoing planned surgery, were included between September 2015 and February 2017. Intraoperative bi-frontal electroencephalograms were recorded. Occurrence and duration of Burst Suppression periods were visually analysed. Emergence delirium was assessed using the Pediatric Assessment of Emergence Delirium Score.
RESULTS:
From 97 children being analysed within this study, 40 children developed emergence delirium, and 57 children did not. Overall 52% of the children displayed intraoperative Burst Suppression periods; however, occurrence and duration of Burst Suppression (Emergence delirium group 55% / 261 + 462 s vs. Non-emergence delirium group 49% / 318 + 531 s) did not differ significantly between both groups.
CONCLUSIONS:
Our data reveal no correlation between the occurrence and duration of intraoperative Burst Suppression activity and the incidence of emergence delirium. Burst Suppression occurrence is frequent; however, it does not seem to have an unfavourable impact on cerebral function at emergence from general anaesthesia in children.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
high dose opiates
en
dc.subject
Paediatrics: pre-operative anxiety
en
dc.subject
burst suppression
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Emergence delirium in children is not related to intraoperative burst suppression – prospective, observational electrography study
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
146
dcterms.bibliographicCitation.doi
10.1186/s12871-019-0819-2
dcterms.bibliographicCitation.journaltitle
BMC Anesthesiology
dcterms.bibliographicCitation.originalpublishername
BMC
dcterms.bibliographicCitation.volume
19
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
31395011
dcterms.isPartOf.eissn
1471-2253