dc.contributor.author
Weippert, Matthias
dc.contributor.author
Divchev, Dimitar
dc.contributor.author
Schmidt, Paul
dc.contributor.author
Gettel, Hannes
dc.contributor.author
Neugebauer, Antina
dc.contributor.author
Behrens, Kristin
dc.contributor.author
Wolfarth, Bernd
dc.contributor.author
Braumann, Klaus-Michael
dc.contributor.author
Nienaber, Christoph A.
dc.date.accessioned
2018-06-08T11:09:44Z
dc.date.available
2017-03-10T09:09:22.936Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/21730
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-25018
dc.description.abstract
Regular physical exercise can positively influence cardiac function; however,
investigations have shown an increase of myocardial damage biomarkers after
acute prolonged endurance exercises. We investigated the effect of repeated
sprint vs. moderate long duration exercise on markers of myocardial necrosis,
as well as cardiac dimensions and functions. Thirteen healthy males performed
two different running sessions (randomized, single blinded cross-over design):
60 minutes moderate intensity continuous training (MCT, at 70% of peak heart
rate (HRpeak)) and two series of 12 × 30-second sprints with set recovery
periods in-between (RST, at 90% HRpeak). Venous blood samples for cardiac
troponin T (cTnT), creatine kinase (CK) and MB isoenzyme (CK-MB) were taken 1
and 4 hours after exercise sessions. After each session electrocardiographic
(ECG) and transthoracic echocardiographic (TTE) data were recorded. Results
showed that all variables - average heart rate, serum lactate concentration
during RST, subjective exertion and cTnT after RST - were significantly higher
compared to MCT. CK and CK-MB significantly increased regardless of exercise
protocol, while ECG and TTE indicated normal cardiac function. Our results
provide evidence that RST contributes significantly to cTnT and CK release.
This biomarker increase seems to reflect a physiological rather than a
pathological phenomenon in healthy, exercising subjects.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Cardiovascular biology
dc.subject
Diagnostic markers
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Cardiac troponin T and echocardiographic dimensions after repeated sprint vs.
moderate intensity continuous exercise in healthy young males
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Scientific Reports. - 6 (2016), Artikel Nr. 24614
dcterms.bibliographicCitation.doi
10.1038/srep24614
dcterms.bibliographicCitation.url
http://www.nature.com/articles/srep24614
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000026596
refubium.note.author
Der Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000007871
dcterms.accessRights.openaire
open access