dc.contributor.author
Volkmann, M.
dc.contributor.author
Steiner, J. M.
dc.contributor.author
Fosgate, G. T.
dc.contributor.author
Zentek, J.
dc.contributor.author
Hartmann, S.
dc.contributor.author
Kohn, B.
dc.date.accessioned
2018-06-08T10:33:23Z
dc.date.available
2017-09-28T10:27:26.118Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/20648
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-23949
dc.description.abstract
Background Chronic diarrhea (CD) is common in dogs, and information on
frequency and distribution of primary and secondary causes is lacking.
Objectives To evaluate underlying causes and predictors of outcome in dogs
with CD. Animals One hundred and thirty-six client-owned dogs with CD (≥3
weeks duration). Methods Retrospective review of medical records (Small Animal
Clinic, Freie Universität Berlin, Germany, 09/2009-07/2011). Quantification of
final diagnoses and comparison of clinical aspects including disease severity
and clinicopathological abnormalities among dogs with clinical remission
(either complete [gastrointestinal signs absent] or partial [clinical
improvement of gastrointestinal signs and reduced episodes with shortened
duration]), and those without recovery. Results Ninety percent of dogs were
diagnosed with a primary enteropathy: inflammatory (71%; of those 66% dietary
responsive, 23% idiopathic, 11% antibiotic responsive), infectious (13%),
neoplastic (4%), and in one dog each mechanical disease or systemic
vasculitis. Secondary causes were diagnosed in 10% of dogs: exocrine
pancreatic (6%), endocrine (2%), and in one dog each hepatic, renal, and
cardiac disease. In total, 87% of dogs had clinical remission, whereas 13%
died or did not respond to treatment: Lack of recovery was frequently recorded
for dogs with primary inflammatory (idiopathic) or neoplastic disease and was
significantly associated with increased disease severity scores (P = .005),
anemia (hematocrit < 40%, P < .001), severe hypoalbuminemia (serum albumin
<2.0 g/dL, P = .008), and severe hypocobalaminemia (serum cobalamin
concentration <200 pg/mL, P = .006). Conclusions and clinical importance
Inflammatory enteropathies and particularly those of dietary origin were the
most common causes of CD in dogs. Findings support the usefulness of
hematocrit, and serum albumin and cobalamin concentration as prognostic
markers in dogs with CD.
en
dc.rights.uri
http://creativecommons.org/licenses/by-nc/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft
dc.title
Chronic Diarrhea in Dogs – Retrospective Study in 136 Cases
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Journal of Veterinary Internal Medicine. - 31 (2017), 4, S. 1043–1055
dcterms.bibliographicCitation.doi
10.1111/jvim.14739
dcterms.bibliographicCitation.url
http://onlinelibrary.wiley.com/doi/10.1111/jvim.14739/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+7th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+08.00+EDT+%2F+13.00+BST+%2F+17%3A30+IST+%2F+20.00+SGT+and+Sunday+8th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+06.00+EDT+%2F+11.00+BST+%2F+15%3A30+IST+%2F+18.00+SGT+for+essential+maintenance.+Apologies+for+the+inconvenience+caused+.
refubium.affiliation
Veterinärmedizin
de
refubium.mycore.fudocsId
FUDOCS_document_000000028048
refubium.note.author
Der Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000008806
dcterms.accessRights.openaire
open access