dc.contributor.author
Umwali, Aurore
dc.contributor.author
Askar, Haitham
dc.contributor.author
Paris, Sebastian
dc.contributor.author
Schwendicke, Falk
dc.date.accessioned
2018-06-08T07:16:08Z
dc.date.available
2016-07-01T11:44:55.482Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/17537
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-21421
dc.description.abstract
Selectively excavated carious lesions remain radiographically detectable.
Radiopaque tagging could resolve the resulting diagnostic uncertainty. We
aimed to evaluate if tagging depends on lesions depths, is antibacterial, or
affects dentin bond-strengths. Artificial lesions (depth-range: 152–682 μm, n
= 34/group) were induced in human dentin samples, evaluated using wavelength-
independent microradiography, treated with one of two tagging materials (70%
SnCl2, 30% SnF2) and re-evaluated. To evaluate antimicrobial effects, 40
dentin samples were submitted to a Lactobacillus rhamnosus invasion-model.
Infected samples were treated with placebo, 0.2% chlorhexidine, SnCl2, SnF2 (n
= 10/group). Dentin was sampled and colony-forming units/mg determined. Micro-
tensile bond-strengths of adhesive restorations (OptiBond FL, Filtek Z250) to
tagged or untagged, sound and carious dentin were assessed (n = 12/group).
Tagged surfaces were evaluated microscopically and via energy-dispersive X
-ray-spectroscopy (EDS). Tagging effects of both materials decreased with
increasing lesion depths (p < 0.001). Un-/chlorhexidine-treated dentin
contained significantly more viable bacteria (median 7.3/3.7 × 105 CFU/mg)
than tagged dentin (no CFU detectable, p < 0.001). Tagging decreased bond
strengths (p < 0.001) on sound (−22%/−33% for SnCl2/SnF2) and carious dentin
(−50%/−54%). This might be due to widespread tin chloride or fluoride
precipitation, as detected via microscopy and EDS. While radiopaque tagging
seems beneficial, an optimized application protocol needs to be developed
prior clinical use.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Radiographic, antibacterial and bond-strength effects of radiopaque caries
tagging
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Scientific Reports. - 6 (2016), Artikel Nr. 27319
dcterms.bibliographicCitation.doi
10.1038/srep27319
dcterms.bibliographicCitation.url
http://www.nature.com/articles/srep27319
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000024937
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006715
dcterms.accessRights.openaire
open access