dc.contributor.author
Haimerl, Peggy
dc.contributor.author
Arlt, Sebastian Patrick
dc.contributor.author
Heuwieser, Wolfgang
dc.date.accessioned
2018-06-08T04:10:56Z
dc.date.available
2014-04-28T10:32:04.087Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/16751
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-20932
dc.description.abstract
The objective of this study was to evaluate the quality and comparability of
published literature, and to summarize the effect of prostaglandin F(2α)
(PGF(2α)) for the treatment of endometritis. It has been postulated that there
is a dearth of high-level evidence-based research results in veterinary
medicine. Also, there is a marked variation in the quality of studies in
veterinary and animal science. Post-partum uterine infections occur commonly
in dairy cattle and are reported to have a negative impact on reproductive
performance. A comprehensive literature search was conducted utilizing online
databases revealing a total of 2723 references. After applying specific
exclusion criteria, a total of 68 trials were eligible for further analysis.
These articles were evaluated utilizing specific parameters listed in an
evaluation form such as randomization and the involvement of control groups.
The analysis revealed that more than half of the trials (51·5%) were at least
20 years old. Furthermore, we found that about one third (36·8%) of all trials
were controlled and randomized, while 3 of those (4·4%) were also blinded. Of
those trials which calculated a calving-to-conception interval (n=30), 50% of
the authors claimed an improvement, which was statistically significant in
23·3% of the cases. We conclude that there is a wide discrepancy between
research results investigating the efficacy of PGF(2α).
de
dc.rights.uri
http://journals.cambridge.org/action/displaySpecialPage?pageId=4676#
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft
dc.title
Evidence-based medicine
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Journal of Dairy Research. - 79 (2012), 3, S. 287-296
dc.identifier.sepid
20557
dc.title.subtitle
quality and comparability of clinical trials investigating the efficacy of
prostaglandin F2α for the treatment of bovine endometritis
dcterms.bibliographicCitation.doi
10.1017/S002202991200012X
dcterms.bibliographicCitation.url
http://dx.doi.org/10.1017/S002202991200012X
refubium.affiliation
Veterinärmedizin
de
refubium.affiliation.other
Tierklinik für Fortpflanzung
refubium.mycore.fudocsId
FUDOCS_document_000000020233
refubium.note.author
Verlags-PDF darf nach 12 Monaten verwendet werden:
http://www.sherpa.ac.uk/romeo/issn/0022-0299/
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000003495
dcterms.accessRights.openaire
open access
dcterms.isPartOf.issn
0022-0299