dc.contributor.author
Alvarado-Esquivel, Cosme
dc.contributor.author
Pacheco-Vega, Sandy Janet
dc.contributor.author
Hernández-Tinoco, Jesús
dc.contributor.author
Salcedo-Jáquez, Misael
dc.contributor.author
Sánchez-Anguiano, Luis Francisco
dc.contributor.author
Berumen-Segovia, Luis Omar
dc.contributor.author
Rábago-Sánchez, Elizabeth
dc.contributor.author
Liesenfeld, Oliver
dc.date.accessioned
2018-06-08T04:09:02Z
dc.date.available
2015-03-13T10:19:33.556Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/16680
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-20861
dc.description.abstract
Background Infection with Toxoplasma gondii can be acquired via the ingestion
of undercooked or raw meat containing tissue cysts, or via ingestion of water
contaminated with oocysts. Professional long distance truck driving may have
epidemiological importance for food-borne infections since drivers eat out of
home and in places where hygiene and cooking practices are uncertain. We aimed
to determine whether interstate truck drivers in Durango, Mexico have an
increased risk of infection with T. gondii as indicated by seropositivity; and
to determine the socio-demographic, work, clinical, and behavioral
characteristics associated with T. gondii seropositivity in interstate truck
drivers. Methods Through a case–control study design, 192 truck drivers and
192 controls from the general population of the same region matched by gender
and age were examined with enzyme-linked immunoassays for the presence of
anti-Toxoplasma IgG and IgM antibodies. Socio-demographic, work, clinical and
behavioral characteristics from the truck drivers were obtained. Results
Anti-T. gondii IgG antibodies were found in 23 (12.0%) of 192 truck drivers
and in 13 (6.8%) of 192 controls (OR = 21.0; 95% CI: 1.23-358.38; P = 0.002).
Anti-T. gondii IgM antibodies were found in 7 (3.6%) cases and in 7 (3.6%)
controls (P = 1.00). The seroprevalence of T. gondii infection was higher in
drivers with reflex impairment than in those without this impairment (4/13,
30.8% vs 19/179, 10.6%, respectively; P = 0.05), and in drivers with hearing
impairment than in those without this impairment (3/7, 42.9% vs 20/185, 10.8%,
respectively; P = 0.03). Multivariate analysis of work and behavioral
characteristics of truck drives showed positive associations of T. gondii
exposure with trips to the south of Mexico (OR = 3.11; 95% CI: 1.02-9.44; P =
0.04) and consumption of horse meat (OR = 5.18; 95% CI: 1.62-16.55; P =
0.005). Conclusions Results suggest that interstate truck drivers may have an
increased risk for T. gondii infection, and that T. gondii exposure may be
impacting neurological functions in truck drivers. Contributing factors for T.
gondii exposure should be taken into account for the design of optimal
prevention measures against T. gondii infection.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
dc.title
Toxoplasma gondii infection in interstate truck drivers
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Parasites & Vectors. - 8 (2015), 1, Artikel Nr. 77
dc.title.subtitle
a case–control seroprevalence study
dcterms.bibliographicCitation.doi
10.1186/s13071-015-0690-z
dcterms.bibliographicCitation.url
http://www.parasitesandvectors.com/content/8/1/77
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000022042
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000004669
dcterms.accessRights.openaire
open access
dcterms.isPartOf.issn
1756-3305