dc.contributor.author
Alvarado-Esquivel, Cosme
dc.contributor.author
Rascon-Careaga, Antonio
dc.contributor.author
Hernandez-Tinoco, Jesus
dc.contributor.author
Corella-Madueno, Maria Alba Guadalupe
dc.contributor.author
Francisco Sanchez-Anguiano, Luis
dc.contributor.author
Aldana-Madrid, Maria Lourdes
dc.contributor.author
Almada-Balderrama, Gerardo Javier
dc.contributor.author
Nunez-Aguirre, Alan Daniel
dc.contributor.author
Liesenfeld, Oliver
dc.date.accessioned
2018-06-08T03:42:44Z
dc.date.available
2016-08-12T11:49:58.363Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15776
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19963
dc.description.abstract
Objectives We sought to determine the prevalence of anti-Toxoplasma gondii
antibodies in Yoremes and to identify associations of T. gondii exposure with
sociodemographic, clinical and behavioural characteristics of Yoremes. Design
A cross-sectional survey. Setting Yoremes were enrolled in the locality of
Tierra Blanca in the municipality of Navojoa in Sonora State, Mexico.
Participants We studied 200 Yoremes (Mayos); they are an indigenous ethnic
group living in a coastal region in northwestern Mexico. Primary and secondary
outcome measures We assessed the prevalence of anti-Toxoplasma IgG and IgM
antibodies in participants using enzyme-linked immunoassays. We used a
standardised questionnaire to obtain the characteristics of Yoremes. The
association of T. gondii exposure and Yoremes’ characteristics was assessed by
bivariate and multivariate analyses. Results Of the 200 Yoremes studied (mean
age: 31.50±18.43 years), 26 (13.0%) were positive for anti-T. gondii IgG
antibodies and 19 (73.1%) of them were also positive for anti-T. gondii IgM
antibodies. Seroprevalence of T. gondii infection did not vary with sex,
educational level, occupation or socioeconomic status. In contrast,
multivariate analysis of sociodemographic and behavioural characteristics
showed that T. gondii exposure was associated with increasing age (OR=1.02;
95% CI 1.00 to 1.04; p=0.03) and consumption of squirrel meat (OR=4.99; 95% CI
1.07 to 23.31; p=0.04). Furthermore, seroprevalence of T. gondii infection was
significantly higher in Yoremes with a history of lymphadenopathy (p=0.03) and
those suffering from frequent abdominal pain (p=0.03). In women, T. gondii
exposure was associated with a history of caesarean sections (p=0.03) and
miscarriages (p=0.02). Conclusions We demonstrate, for the first time,
serological evidence of T. gondii exposure among Yoremes in Mexico. Results
suggest that infection with T. gondii might be affecting the health of
Yoremes. Results may be useful for an optimal design of preventive measures
against T. gondii infection.
en
dc.rights.uri
http://creativecommons.org/licenses/by-nc/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Seroprevalence and correlates of Toxoplasma gondii infection in Yoremes
(Mayos) in Mexico
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
BMJ Open. - 6 (2016), 5, Artikel Nr. e010218
dc.title.subtitle
a cross-sectional study
dcterms.bibliographicCitation.doi
10.1136/bmjopen-2015-010218
dcterms.bibliographicCitation.url
http://bmjopen.bmj.com/content/6/5/e010218
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000025073
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006819
dcterms.accessRights.openaire
open access