dc.contributor.author
Greyling, Arno
dc.contributor.author
Ras, Rouyanne T.
dc.contributor.author
Zock, Peter L.
dc.contributor.author
Lorenz, Mario
dc.contributor.author
Hopman, Maria T.
dc.contributor.author
Thijssen, Dick H. J.
dc.contributor.author
Draijer, Richard
dc.date.accessioned
2018-06-08T03:42:02Z
dc.date.available
2014-09-17T07:24:58.988Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15751
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19938
dc.description.abstract
Objective Epidemiological evidence has linked consumption of black tea,
produced from Camellia sinensis, with a reduced risk of cardiovascular
diseases. However, intervention studies on the effects of tea consumption on
blood pressure (BP) have reported inconsistent results. Our objective was to
conduct a systematic literature review with meta-analysis of controlled human
intervention studies examining the effect of tea consumption on BP. Methods We
systematically searched Medline, Biosis, Chemical Abstracts and EMBASE
databases through July 2013. For inclusion, studies had to meet the following
pre-defined criteria: 1) placebo controlled design in human adults, 2) minimum
of 1 week black tea consumption as the sole intervention, 3) reported effects
on systolic BP (SBP) or diastolic BP (DBP) or both. A random effects model was
used to calculate the pooled overall effect of black tea on BP. Results Eleven
studies (12 intervention arms, 378 subjects, dose of 4–5 cups of tea) met our
inclusion criteria. The pooled mean effect of regular tea ingestion was −1.8
mmHg (95% CI: −2.8, −0.7; P = 0.0013) for SBP and −1.3 mmHg (95% CI: −1.8,
−0.8; P<0.0001) for DBP. In covariate analyses, we found that the method of
tea preparation (tea extract powders versus leaf tea), baseline SBP and DBP,
and the quality score of the study affected the effect size of the tea
intervention (all P<0.05). No evidence of publication bias could be detected.
Conclusions Our meta-analysis indicates that regular consumption of black tea
can reduce BP. Although the effect is small, such effects could be important
for cardiovascular health at population level.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
The Effect of Black Tea on Blood Pressure
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
PLoS ONE. - 9 (2014), 7, Artikel Nr. e103247
dc.title.subtitle
A Systematic Review with Meta-Analysis of Randomized Controlled Trials
dcterms.bibliographicCitation.doi
10.1371/journal.pone.0103247
dcterms.bibliographicCitation.url
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0103247
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000020974
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000003920
dcterms.accessRights.openaire
open access