dc.contributor.author
Pinho, Marcos D.
dc.contributor.author
Erol, Erdal
dc.contributor.author
Ribeiro-Goncalves, Bruno
dc.contributor.author
Mendes, Catarina I.
dc.contributor.author
Carrico, Joao A.
dc.contributor.author
Matos, Sandra C.
dc.contributor.author
Luebke-Becker, Antina
dc.contributor.author
Wieler, Lothar H.
dc.contributor.author
Melo-Cristino, Jose
dc.contributor.author
Ramirez, Mario
dc.date.accessioned
2018-06-08T03:36:44Z
dc.date.available
2016-09-15T11:11:49.547Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15562
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19750
dc.description.abstract
The pathogenic role of beta-hemolytic Streptococcus dysgalactiae in the equine
host is increasingly recognized. A collection of 108 Lancefield group C (n =
96) or L (n = 12) horse isolates recovered in the United States and in three
European countries presented multilocus sequence typing (MLST) alleles,
sequence types and emm types (only 56% of the isolates could be emm typed)
that were, with few exceptions, distinct from those previously found in human
Streptococcus dysgalactiae subsp. equisimilis. Characterization of a subset of
horse isolates by multilocus sequence analysis (MLSA) and 16S rRNA gene
sequence showed that most equine isolates could also be differentiated from S.
dysgalactiae strains from other animal species, supporting the existence of a
horse specific genomovar. Draft genome information confirms the
distinctiveness of the horse genomovar and indicates the presence of
potentially horse-specific virulence factors. While this genomovar represents
most of the isolates recovered from horses, a smaller MLST and MLSA defined
sub-population seems to be able to cause infections in horses, other animals
and humans, indicating that transmission between hosts of strains belonging to
this group may occur.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
dc.title
Beta-hemolytic Streptococcus dysgalactiae strains isolated from horses are a
genetically distinct population within the Streptococcus dysgalactiae taxon
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Scientific Reports. - 6 (2016), Artikel Nr. 31736
dcterms.bibliographicCitation.doi
10.1038/srep31736
dcterms.bibliographicCitation.url
http://www.nature.com/articles/srep31736
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000025355
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006951
dcterms.accessRights.openaire
open access