dc.contributor.author
Walker, Karolina A.
dc.contributor.author
Stumbe, Jean-Francois
dc.contributor.author
Haag, Rainer
dc.date.accessioned
2018-06-08T03:35:56Z
dc.date.available
2016-07-15T12:02:00.002Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15526
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19714
dc.description.abstract
A water-soluble, core-multishell (CMS) nanocarrier based on a new
hyperbranched polyester core building block was synthesized and characterized
towards drug transport and degradation of the nanocarrier. The hydrophobic
drug dexamethasone was encapsulated and the enzyme-mediated biodegradability
was investigated by NMR spectroscopy. The new CMS nanocarrier can transport
one molecule of dexamethasone and degrades within five days at a skin
temperature of 32 °C to biocompatible fragments.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
500 Naturwissenschaften und Mathematik::540 Chemie
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
dc.title
Polyester-Based, Biodegradable Core-Multishell Nanocarriers for the Transport
of Hydrophobic Drugs
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Polymers. - 8 (2016), 5, Artikel Nr. 192
dcterms.bibliographicCitation.doi
10.3390/polym8050192
dcterms.bibliographicCitation.url
http://www.mdpi.com/2073-4360/8/5/192
refubium.affiliation
Biologie, Chemie, Pharmazie
de
refubium.mycore.fudocsId
FUDOCS_document_000000025007
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006779
dcterms.accessRights.openaire
open access