dc.contributor.author
Iggena, Deetje
dc.contributor.author
Klein, Charlotte
dc.contributor.author
Garthe, Alexander
dc.contributor.author
Winter, York
dc.contributor.author
Kempermann, Gerd
dc.contributor.author
Steiner, Barbara
dc.date.accessioned
2018-06-08T03:33:09Z
dc.date.available
2015-10-02T11:39:28.259Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15424
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19612
dc.description.abstract
In the context of television consumption and its opportunity costs the
question arises how far experiencing mere representations of the outer world
would have the same neural and cognitive consequences than actively
interacting with that environment. Here we demonstrate that physical
interaction and direct exposition are essential for the beneficial effects of
environmental enrichment. In our experiment, the mice living in a simple
standard cage placed in the centre of a large enriched environment only
indirectly experiencing the stimulus-rich surroundings (IND) did not display
increased adult hippocampal neurogenesis. In contrast, the mice living in and
directly experiencing the surrounding enriched environment (DIR) and mice
living in a similar enriched cage containing an uninhabited inner cage (ENR)
showed enhanced neurogenesis compared to mice in control conditions (CTR).
Similarly, the beneficial effects of environmental enrichment on learning
performance in the Morris Water maze depended on the direct interaction of the
individual with the enrichment. In contrast, indirectly experiencing a
stimulus-rich environment failed to improve memory functions indicating that
direct interaction and activity within the stimulus-rich environment are
necessary to induce structural and functional changes in the hippocampus.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Only watching others making their experiences is insufficient to enhance adult
neurogenesis and water maze performance in mice
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Scientific Reports. - 5 (2015), Artikel Nr. 14141
dcterms.bibliographicCitation.doi
10.1038/srep14141
dcterms.bibliographicCitation.url
http://www.nature.com/articles/srep14141
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000023220
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000005483
dcterms.accessRights.openaire
open access