Marx, Florian M.
Glaser- Paschke, Gisela
Background In Western Europe, migrants constitute an important risk group for
tuberculosis, but little is known about successive generations of migrants. We
aimed to characterize migration among tuberculosis cases in Berlin and to
estimate annual rates of tuberculosis in two subsequent migrant generations.
We hypothesized that second generation migrants born in Germany are at higher
risk of tuberculosis compared to native (non-migrant) residents. Methods A
prospective cross-sectional study was conducted. All tuberculosis cases
reported to health authorities in Berlin between 11/2010 and 10/2011 were
eligible. Interviews were conducted using a structured questionnaire including
demographic data, migration history of patients and their parents, and
language use. Tuberculosis rates were estimated using 2011 census data.
Results Of 314 tuberculosis cases reported, 154 (49.0%) participated. Of
these, 81 (52.6%) were first-, 14 (9.1%) were second generation migrants, and
59 (38.3%) were native residents. The tuberculosis rate per 100,000
individuals was 28.3 (95CI: 24.0–32.6) in first-, 10.2 (95%CI: 6.1–16.6) in
second generation migrants, and 4.6 (95%CI: 3.7–5.6) in native residents. When
combining information from the standard notification variables country of
birth and citizenship, the sensitivity to detect second generation migration
was 28.6%. Conclusions There is a higher rate of tuberculosis among second
generation migrants compared to native residents in Berlin. This may be
explained by presumably frequent contact and transmission within migrant
populations. Second generation migration is insufficiently captured by the
surveillance variables country of birth and citizenship. Surveillance systems
in Western Europe should allow for quantifying the tuberculosis burden in this
important risk group.
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
Higher Rate of Tuberculosis in Second Generation Migrants Compared to Native
Residents in a Metropolitan Setting in Western Europe
PLoS ONE. - 10 (2015), 6, Artikel Nr. e0119693
Charité - Universitätsmedizin Berlin
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.