Title:
One-pot synthesis of doxorubicin-loaded multiresponsive nanogels based on
hyperbranched polyglycerol
Author(s):
Sousa-Herves, Ana; Wedepohla, Stefanie; Calderón, Marcelo
Year of publication:
2015
Available Date:
2015-12-21T13:31:39.721Z
Abstract:
Doxorubicin-loaded nanogels with multiresponsive properties are prepared using
hyperbranched polyglycerol as a biocompatible scaffold. The nanogels are
synthesized in a single step combining free-radical polymerization and a mild
nanoprecipitation technique. The nanogels respond to different biological
stimuli such as low pH and reductive environments, resulting in a more
efficient cell proliferation inhibition in A549 cells.
DDC-Classification:
572 Biochemie
Publication Type:
Wissenschaftlicher Artikel
Also published in:
Chem. Commun., 2015, 51, 5264
URL of the Original Publication:
DOI of the Original Publication:
Department/institution:
Biologie, Chemie, Pharmazie