dc.contributor.author
Stuijvenberg, Margriet van
dc.contributor.author
Stam, José
dc.contributor.author
Grüber, Christoph
dc.contributor.author
Mosca, Fabio
dc.contributor.author
Arslanoglu, Sertac
dc.contributor.author
Chirico, Gaetano
dc.contributor.author
Braegger, Christian P.
dc.contributor.author
Riedler, Josef
dc.contributor.author
Boehm, Günther
dc.contributor.author
Sauer, Pieter J. J.
dc.date.accessioned
2018-06-08T02:55:39Z
dc.date.available
2015-07-16T10:46:45.713Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/14153
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-18350
dc.description.abstract
This is a follow up study of a multicenter randomised placebo-controlled trial
in seven centres in five West European countries. The RCT assessed the effect
of infant formula supplemented with a mixture of prebiotics (with neutral
short-chain and long-chain oligosaccharides and pectin-derived acidic
oligosaccharides) during infancy in term-born children (n=1130). In the
follow-up study 672 children (60% of the study population) participated: 232
(56%) from the prebiotics group (PG), 243 (58%) from the control group (CG),
and 197 (66%) from the non-randomised breast-fed group (BG). The primary
outcome was the occurrence of febrile episodes at three to five years of age
prospectively documented by the parents: in the PG 1.17 (interquartile range
0.50-2.08) episodes per year versus 1.20 (0.52-2.57) in the CG; and 1.48
(0.65-2.60) in the BG. This specific prebiotics mixture given during infancy
in healthy non-atopic subjects does not decrease febrile episodes and
therefore seems not to prevent infection between their third and fifth
birthday.
de
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Similar Occurrence of Febrile Episodes Reported in Non-Atopic Children at
Three to Five Years of Age after Prebiotics Supplemented Infant Formula
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
PLoS ONE. - 10 (2015), 6, Artikel Nr. e0129927
dcterms.bibliographicCitation.doi
10.1371/journal.pone.0129927
dcterms.bibliographicCitation.url
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129927
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000022829
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000005207
dcterms.accessRights.openaire
open access