dc.contributor.author
Krug, Susanne M.
dc.date.accessioned
2025-11-19T12:42:53Z
dc.date.available
2025-11-19T12:42:53Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/50435
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-50162
dc.description.abstract
Intestinal barrier studies often employ cell lines having limited cell
type representation compared to native tissue. Organoids comprising
most intestinal cell types better mimic in vivo conditions. However, 3D
organoids pose challenges for barrier analysis. Thus, organoid-derived
monolayers were generated that closely resemble donor tissue under
optimized conditions, making them suitable for tissue-specifi c investi gation. Further developments will incorporate additional intestinal
compartments.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
darmbarriere
de
dc.subject
gastrointestinaltrakt
de
dc.subject
luminalen pathogenen
de
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Von 3D zu 2D: Organoid-basierte Monolayer als Modell der Darmbarriere
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s12268-023-2040-6
dcterms.bibliographicCitation.journaltitle
BIOspektrum
dcterms.bibliographicCitation.number
7
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.volume
29
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.issn
0947-0867
dcterms.isPartOf.eissn
1868-6249
