Title:
Glycan-induced fluorescence enhancement using a molecular rotor–boronic acid conjugate
Author(s):
Oloub, Mandana; Koçak, Alen; Baydaroğlu, Cihan; Homer, Amal K.; Telschow, Florian; Loyo-Cruz, Victor M.; Trunschke, Sebastian; Vos, Gaël M.; Pagel, Kevin; Gradzielski, Michael; Alexiev, Ulrike; Seitz, Oliver
Year of publication:
2025
Available Date:
2025-09-12T04:09:59Z
Abstract:
Fluorescent molecular rotors (FMRs) are known for their sensitivity to changes in viscosity and confinement. Here, we show that a boronic acid conjugate of the rotor dye CCVJ exhibits strong enhancements in fluorescence upon binding to complex glycans. Glycan-induced fluorescence enhancement (GIFE) operates at low and high viscosity.
Part of Identifier:
ISSN (print): 1359-7345
e-ISSN (online): 1364-548X
Keywords:
fluorescent molecular rotors
boronic acid conjugate
fluorescence enhancement
DDC-Classification:
540 Chemie und zugeordnete Wissenschaften
Publication Type:
Wissenschaftlicher Artikel
URL of the Original Publication:
DOI of the Original Publication:
Journaltitle:
Chemical Communications
Department/institution:
Biologie, Chemie, Pharmazie
Institut für Chemie und Biochemie
